Chemistry @ Dal
    Dalhousie University

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Prodigiosenes Publication

 

  

Please also see:   http://pubs.rsc.org/en/content/articlelanding/2013/ob/c2ob26535d  

 

Prodigiosenes, possessing a 4-methoxypyrrolyldipyrrin skeleton, are   known for their anti-cancer activity.
Structural modification of the   C-ring resulted in a series of prodigiosenes that displayed promising
activity against leukemia cell lines during in vitro analysis against   the NCI 60 cancer cell line panel.
Further in vivo studies of these   compounds using the zebrafish model showed persistence of
anti-leukemia properties in human K562 chronic myelogenous leukemia   cells.